Greg Monroe had 15 points and nine rebounds and rookie Andre Drummond added a double-double and the Detroit Pistons ended a six-game losing streak with a 100-68 rout Friday night.
The Pistons, who never trailed, got 15 points from Brandon Knight and 11 points and a career-high 14 rebounds from Drummond. Detroit hadn't beaten anyone other than the Cavaliers since late November.
The teams meet again Saturday night in the nation's capital, but the Wizards will have to play a much better game to have a shot at splitting the home-and-home series.
Washington only dressed nine players, with John Wall, Trevor Ariza, Bradley Beal and Nene among the unavailable players, and lost their sixth straight.
Jordan Crawford led Washington with 20 points, but two other players reached double figures.